CBDa, CBGa, CBD & CBG: What Does It All Mean?

When Harvard chemist, Roger Adams first extracted the CBD compound from the Cannabis plant in 1940, he had no idea of what he had started. However, it wasn’t until the 1960s that CBD oil was released for therapeutic use and 1980 when it became semi-mainstream as an effective treatment for epilepsy. Well, we have come a long way and the cannabinoid arena has expanded even further. In this article, we will focus on the benefits of CBG, CBGa, CBDa, and their multiple uses—including fighting COVID-19.

An Overview of the Differences in Cannabinoids

What many people outside of the plant-based therapy field do not realize is that cannabinoids exist within the human biological structure. Our endocannabinoid system is a network of receptors located throughout the body, including the central nervous and immune systems. Cannabinoids are compounds that interacts with the ECS benefitting the human body in several ways—including mood, pain sensation, appetite, and memory.

There are two main receptors within our endocannabinoid system. CB1 communicates with our brain and central nervous system while CB2 interacts with our immune system. Cannabinoids, CBD, CBDa, CBG, and CBGa mimic our cannabinoid system and trigger receptors which can result in remarkable health benefits. However, each cannabinoid compound reacts differently and when combined can have even more benefits.

The overwhelming difference between cannabinoids is how each cannabinoid is produced and extracted. CBD is the most abundant cannabinoid found throughout the hemp plant, but CBG can only be extracted during the bloom.

CBDa is the pre-cursor to CBD before it is decarboxylated or heated resulting in a different molecular structure which is CBD. It is only new research that shows CBDa as effective for producing health benefits and treatments.

Benefits of CBG

CBG binds to both the CB1 and the CB2 receptors which means the CBG compound can benefit both the nervous system and the immune system. It has antibacterial, antifungal, and antiparasitic properties. It also reduces inflammation and pain without causing psycho-activity. It has also been used to treat cancer, glaucoma, Huntington’s disease, and Alzheimer’s.

  • Inflammation and Pain
  • Antibacterial, Anti-fungal, and antimicrobial
  • Anxiety and Anti-depressant
  • Neuroprotective properties
  • Cancer Treatment
  • Bladder Dysfunction
  • Glaucoma

Benefits of CBGa

CBGa is the precursor to CBG and is still in research to identify a comprehensive understanding of all the benefits but currently, we know that it is been effective for treating complications associated with diabetes, and heart disease. It has been shown to curb the cancer cell cycle in the colon and has the potential to slow or prevent the growth of polyps.

  • Addressing Metabolic Disorders like diabetes and high cholesterol
  • Cardiovascular Disease
  • Targeting Colon Cancer

Benefits of CBDa

Like CBGa, CBDa is still in the early phases of research but has already shown to be even more effective than its precursor, CBD.

The British Journal of Pharmacology found that CBDA produces antidepressant effects on rats at doses 10 to 100 times lower than CBD.

CBDa has a direct reaction on the serotonin receptors which means it can be an effective treatment for mood regulations, nausea, intestinal activity, and cancer cell migration. A study in 2012 showed that CBDa stopped cancer cells from migrating which could effectively mean stopping the spread. Overall treatments include:

  • Inflammation and pain
  • Nausea & Vomiting
  • Cancer Cell migration and spread
  • Psychosis

CBD, CBDa and CBGa for fighting COVID-19

Much has been published recently about the effects of hemp compounds and their effects on the COVID-19 disease. A Forbes Magazine article published in January stated that If taken in the right way, CBD might lessen the severity of COVID-19 infection and even prevent the virus’s spread.

“CBD and its metabolite 7-OH-CBD, which is a compound produced after the body processes CBD, can block SARS-Cov-2 infection at early and even later stages of infection”. — researchers, led by academics at the University of Chicago.

The article goes on to say that new anecdotal evidence suggests that people who were prescribed regular high-potency doses of CBD were less likely to contract COVID.

Another study led by Richard van Breemen, a researcher with Oregon State’s Global Hemp Innovation Center, College of Pharmacy, and Linus Pauling Institute, found that CBDa and CBGa bind to the SARS-CoV-2 spike protein, blocking the virus from entering human cells.

A New Tincture with All the Benefits and More

Because the combination of CBDa and CBGa has proven beneficial in terms of immune health, combined with the study conducted by OSU that showed that they can prevent COVID from entering human cells, Kaya Hemp Co. immediately pursued a formulation that would address the new demand.

Introducing our full-spectrum CBD, CBG, CBDa, and CBGa Lemon Ginger SUPPORT tincture (sublingual drops). Our custom formulation includes plant-based Turkey Tail & Reishi Mushrooms, Holy Basil, and Astragalus to help support a healthy immune system and joint health.

Our CBD/CBG/CBDa/CBGa tincture is now available tin 3 potencies and sizes: 750mg oz bottle, 1500mg 1oz bottle, 3000mg 2oz bottle. Visit us in the store or shop online at Kaya Holistic.